A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies.

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Term information

Subsets

3_STAR

database cross reference

PMID:19251032

PMID:12137720

PMID:6069707

Wikipedia:Insulin

PMID:5941964

PMID:25848166

has obo namespace

chebi_ontology

id

CHEBI:145810

imported from

http://purl.obolibrary.org/obo/chebi.owl