A benzazepine that is benazeprilat in which the carboxy group of the 2-amino-4-phenylbutanoic acid moiety has been converted to the corresponding ethyl ester. It is used (generally as its hydrochloride salt) as a prodrug for the angiotensin-converting enzyme inhibitor benazeprilat in the treatment of hypertension and heart failure.

Synonyms: Benazepril [(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid

This is just here as a test because I lose it

Term information

database cross reference
Subsets

3_STAR

charge

0

database cross reference

Wikipedia:Benazepril

Reaxys:4302258

PMID:25738503

KEGG:D07499

Patent:US4410520

PMID:25224804

CAS:86541-75-5

HMDB:HMDB0014682

Patent:EP72352

PMID:25912588

KEGG:C06843

MetaCyc:CPD-15329

DrugBank:DB00542

PMID:25784709

Drug_Central:299

LINCS:LSM-5609

formula

C24H28N2O5

has related synonym

benazepril

benazeprilum

1H-1-Benzazepine-1-acetic acid, 3-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-2,3,4,5-tetrahydro-2-oxo-, (S-(R*,R*))-

has obo namespace

chebi_ontology

id

CHEBI:3011

imported from

http://purl.obolibrary.org/obo/chebi.owl

inchi

InChI=1S/C24H28N2O5/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28)/t19-,20-/m0/s1

inchikey

XPCFTKFZXHTYIP-PMACEKPBSA-N

mass

424.48950

monoisotopicmass

424.19982

smiles

CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCc2ccccc2N(CC(O)=O)C1=O

Term relations

Subclass of: