A benzodiazepine that is 5H-dibenzo[b,e][1,4]diazepine substituted by a chloro group at position 8 and a 4-methylpiperazin-1-yl group at position 11. It is a second generation antipsychotic used in the treatment of psychiatric disorders like schizophrenia.
Synonyms: 8-chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine Clozapine
Term information
- Wikipedia:Clozapine
- CAS:5786-21-0
- PMID:24219174
- PMID:18766167
- Patent:NL293201
- Patent:US3539573
- Beilstein:0764984
- Drug_Central:722
- HMDB:HMDB0014507
- Patent:FR1334944
- PMID:20825390
- Reaxys:764984
- DrugBank:DB00363
- PMID:18690109
- KEGG:C06924
- KEGG:D00283
3_STAR
Drug_Central:722
Patent:FR1334944
KEGG:D00283
PMID:24219174
KEGG:C06924
CAS:5786-21-0
PMID:18690109
PMID:20825390
Beilstein:0764984
Wikipedia:Clozapine
HMDB:HMDB0014507
Patent:NL293201
Patent:US3539573
Reaxys:764984
DrugBank:DB00363
PMID:18766167
InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3