A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom).

Synonyms: LOVASTATIN (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate Lovastatin lovastatin

This is just here as a test because I lose it

Term information

database cross reference
Subsets

3_STAR

charge

0

database cross reference

PMID:7720768

KNApSAcK:C00000547

CAS:75330-75-5

PMID:11483865

PMID:18642339

PMID:11375168

HMDB:HMDB0014372

Patent:WO2013090461

Patent:CN103172602

PMID:11389707

Wikipedia:Lovastatin

PMID:24093797

Reaxys:4720754

Beilstein:3631989

KEGG:C07074

LINCS:LSM-2189

DrugBank:DB00227

PDBeChem:803

KEGG:D00359

Drug_Central:1612

formula

C24H36O5

has related synonym

6alpha-methylcompactin

(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate

Mevacor

2beta,6alpha-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone

MK-803

ML-530B

Mevinolin

has alternative id

CHEBI:6544

CHEBI:40299

has obo namespace

chebi_ontology

id

CHEBI:40303

imported from

http://purl.obolibrary.org/obo/chebi.owl

inchi

InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1

inchikey

PCZOHLXUXFIOCF-BXMDZJJMSA-N

mass

404.53964

monoisotopicmass

404.25627

smiles

[H][C@]12[C@H](C[C@@H](C)C=C1C=C[C@H](C)[C@@H]2CC[C@@H]1C[C@@H](O)CC(=O)O1)OC(=O)[C@@H](C)CC

Term relations

Subclass of: