A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Synonyms: Clomipramine 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine
Term information
- PMID:19747949
- PMID:19810911
- KEGG:D07727
- PDBeChem:CXX
- KEGG:C06918
- PMID:12084414
- Wikipedia:Clomipramine
- PMID:12007764
- DrugBank:DB01242
- Drug_Central:701
- Patent:US3467650
- PMID:16085036
- Patent:CH371799
- CAS:303-49-1
- PMID:17471183
- Reaxys:1323477
- LINCS:LSM-3171
- Beilstein:1323477
3_STAR
KEGG:C06918
Beilstein:1323477
PMID:17471183
CAS:303-49-1
PMID:19747949
Drug_Central:701
PMID:12084414
LINCS:LSM-3171
Wikipedia:Clomipramine
Patent:CH371799
PDBeChem:CXX
Reaxys:1323477
PMID:12007764
Patent:US3467650
PMID:16085036
KEGG:D07727
PMID:19810911
DrugBank:DB01242
3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine
chlorimipramine
3-chloroimipramine
G 34586
monochlorimipramine
3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE
InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3