A 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one substituted by a 2-(diethylamino)ethyl group, 2-fluorophenyl group and chloro group at positions 1, 5 and 7, respectively. It is a partial agonist of GABAA receptors and used for the treatment of insomnia.
Synonyms: 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one
Term information
- PDBeChem:FL7
- KEGG:D00329
- PMID:23035248
- HMDB:HMDB0014828
- PMID:2863335
- Wikipedia:Flurazepam
- PMID:20002022
- CAS:17617-23-1
- PMID:16501350
- Drug_Central:1218
- DrugBank:DB00690
3_STAR
PMID:23035248
PDBeChem:FL7
HMDB:HMDB0014828
CAS:17617-23-1
PMID:2863335
Drug_Central:1218
PMID:20002022
Wikipedia:Flurazepam
DrugBank:DB00690
KEGG:D00329
PMID:16501350
InChI=1S/C21H23ClFN3O/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23/h5-10,13H,3-4,11-12,14H2,1-2H3