A methyl ketone that is 2-butanone in which one of the methyl hydrogens at position 4 is replaced by a 6-methoxy-2-naphthyl group. A prodrug that is converted to the active metabolite, 6-methoxy-2-naphthylacetic acid, following oral administration. It is shown to have a slightly lower risk of gastrointestinal side effects than most other non-steroidal anti-inflammatory drugs.
Term information
- PMID:21650014
- PMID:22977877
- KEGG:D00425
- Reaxys:2103472
- PMID:22298755
- PMID:23806470
- CAS:42924-53-8
- PMID:21898684
- Wikipedia:Nabumetone
- PMID:23129452
- DrugBank:DB00461
- PMID:23020786
- Beilstein:2103472
- PMID:23225308
- PMID:24074034
- PDBeChem:NBO
- PMID:21532165
- PMID:23781476
- PMID:23781467
- Drug_Central:1863
- PMID:21674107
- PMID:22028826
- PMID:23132511
- LINCS:LSM-3453
- PMID:23584048
- PMID:24083957
- HMDB:HMDB0014604
- PMID:22381180
- PMID:22605805
3_STAR
PMID:21532165
LINCS:LSM-3453
PMID:21674107
PMID:21650014
Beilstein:2103472
PMID:23129452
PMID:23781467
CAS:42924-53-8
PMID:22298755
PMID:23225308
PMID:23584048
Wikipedia:Nabumetone
PMID:23020786
KEGG:D00425
PMID:24083957
Drug_Central:1863
PMID:22381180
PMID:23132511
HMDB:HMDB0014604
PMID:24074034
PMID:21898684
PMID:23806470
PMID:22977877
PMID:22605805
PMID:22028826
PDBeChem:NBO
PMID:23781476
Reaxys:2103472
DrugBank:DB00461
Relafen
nabumetonum
nabumetona
4-(6-Methoxy-2-naphthalenyl)-2-butanone
4-(6-Methoxy-2-naphthyl)-2-butanone
nabumetone