A dipeptide that is the prodrug for ramiprilat, the active metabolite obtained by hydrolysis of the ethyl ester group. An angiotensin-converting enzyme (ACE) inhibitor, used to treat high blood pressure and congestive heart failure.
Synonyms: Ramipril (2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
Term information
- PMID:12076194
- PMID:23951921
- PMID:24435506
- PMID:11575208
- PMID:23842829
- PMID:24509355
- PMID:17004100
- PMID:20122169
- PMID:23842688
- PMID:24191305
- Drug_Central:2356
- PMID:17192135
- LINCS:LSM-5950
- Reaxys:4214464
- KEGG:D00421
- CAS:87333-19-5
- PMID:17496463
- Wikipedia:Ramipril
- PMID:11095026
- PMID:24090393
- VSDB:1888
- Beilstein:4214464
- PMID:15110900
- PMID:23747952
- PMID:16144510
- PMID:24452090
- PMID:23557551
- PMID:16734081
- DrugBank:DB00178
- PMID:17903031
- PMID:24048485
- PMID:23713675
- HMDB:HMDB0014324
- PMID:12768220
- PMID:24397981
- PMID:22799880
3_STAR
PMID:11095026
PMID:24191305
Reaxys:4214464
PMID:12768220
Wikipedia:Ramipril
KEGG:D00421
LINCS:LSM-5950
VSDB:1888
Drug_Central:2356
PMID:17192135
Beilstein:4214464
PMID:23842688
PMID:23557551
PMID:12076194
PMID:17004100
PMID:24048485
DrugBank:DB00178
PMID:23842829
PMID:16144510
PMID:16734081
PMID:23951921
PMID:11575208
HMDB:HMDB0014324
PMID:24452090
PMID:23713675
PMID:15110900
PMID:17496463
PMID:24509355
PMID:17903031
PMID:24435506
PMID:20122169
PMID:24090393
PMID:24397981
PMID:23747952
PMID:22799880
CAS:87333-19-5
Ramiprilum
(2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
Altace (TN)
Tritace
ramipril
InChI=1S/C23H32N2O5/c1-3-30-23(29)18(13-12-16-8-5-4-6-9-16)24-15(2)21(26)25-19-11-7-10-17(19)14-20(25)22(27)28/h4-6,8-9,15,17-20,24H,3,7,10-14H2,1-2H3,(H,27,28)/t15-,17-,18-,19-,20-/m0/s1