A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.
Synonyms: (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Sertraline
Term information
- Beilstein:5753709
- Drug_Central:2436
- PMID:21823671
- PMID:19502000
- HMDB:HMDB0005010
- CAS:79617-96-2
- KEGG:C07246
- LINCS:LSM-3843
- KEGG:D02360
- Reaxys:5753709
- Wikipedia:Sertraline
- Patent:US4536518
- DrugBank:DB01104
- PDBeChem:SRE
3_STAR
Beilstein:5753709
CAS:79617-96-2
PMID:19502000
PDBeChem:SRE
KEGG:D02360
Patent:US4536518
LINCS:LSM-3843
Reaxys:5753709
DrugBank:DB01104
PMID:21823671
HMDB:HMDB0005010
KEGG:C07246
Drug_Central:2436
Wikipedia:Sertraline
sertralinum
(1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
(+)-sertraline
cis-(+)-sertraline
CP 51974
(1S,4S)-sertraline
sertralina
sertraline
InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1