A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.
Synonyms: neurotrophin receptor signaling pathway
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There are two classes of receptors for neurotrophins: p75 and the Trk family of tyrosine kinase receptors.