They are a group of drugs that block the normal breakdown of acetylcholine (ACh) into acetate and choline and thereby increase both the levels and duration of actions of acetylcholine found in the central and peripheral nervous system.
Synonyms: EC 3.1.1.8 (cholinesterase) inhibitor therapy cholinesterase inhibitor medication therapy cholinesterase inhibitor drug treatment treatment with EC 3.1.1.8 (cholinesterase) inhibitor
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Neurogenerative diseases such as Alzheimer disease, Parkinson disease, and Lewy body dementia are indications for cholinesterase inhibitor therapy.