MIF
|
OGG_3000004282 |
|
statistical hypothesis test
|
OBI_0000673 |
[A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test.] |
data transformation
|
OBI_0200000 |
[A planned process that produces output data from input data.] |
insulin signaling pathway
|
PW_0000143 |
[Insulin, the peptide hormone, secreted by the pancreatic beta cells, plays essential roles in glucose and energy homeostasis. Insulin signaling activates two main intracellular pathways to regulate carbohydrate and fat metabolism and to prompt glucose absorption in insulin sensitive tissues such as skeletal muscle and adipocytes. Deregulation of the pathway has been associated with a number of conditions, primarily diabetes.] |
pathway
|
PW_0000001 |
[A pathway is a set of inter-connected reactions and interactions whose delineation and scope are used as a model for exploring and studying, describing and understanding the working of and relationships between biomolecules within a context.] |
paroxetine
|
CHEBI_7936 |
[A benzodioxole that consists of piperidine bearing 1,3-benzodioxol-5-yloxy)methyl and 4-fluorophenyl substituents at positions 3 and 4 respectively; the (3S,4R)-diastereomer. Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki = 0.05 nM). Ki values are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity for alpha1-, alpha2- or beta-adrenoceptors, 5-HT2A, 5-HT1A, D2 or H1 receptors at concentrations below 1000 nM, however displays weak affinity for muscarinic ACh receptors (Ki = 42 nM). Antidepressant and anxiolytic in vivo.] |
antidepressant
|
CHEBI_35469 |
[Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.] |
glucocorticoid
|
CHEBI_24261 |
[Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.] |
lipid
|
CHEBI_18059 |
['Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids.] |
Primary Outcome Measure
|
NCIT_C98772 |
[The primary measurement(s) or observation(s) used to measure the effect of experimental variables in a study, or for observational studies, to describe patterns of diseases or traits or associations with exposures, risk factors or treatment. These are the outcome measures used to assess the primary objective(s).] |
SIRT2
|
OGG_3000022933 |
|
amyloid plaque
|
BTO_0002774 |
[A plaque consisting of tangles of amyloid protein in nervous tissue (a pathological mark of Alzheimer's disease).] |
Abnormal nervous system morphology
|
HP_0012639 |
[A structural anomaly of the nervous system.] |
RNA gene
|
OGG_0000000031 |
[a gene that encodes for a RNA] |
gene
|
OGG_0000000002 |
[A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. ] |
PDE5A
|
OGG_3000008654 |
|
heteroatomic molecular entity
|
CHEBI_37577 |
[A molecular entity consisting of two or more chemical elements.] |
polyatomic entity
|
CHEBI_36357 |
[Any molecular entity consisting of more than one atom.] |
halide
|
CHEBI_37578 |
[Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements.] |
halogen molecular entity
|
CHEBI_24471 |
|