CLOCK delta 19 mutant mouse model
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This is just here as a test because I lose it
Term information
CommentOnHierarchy
No reference ontology for OBO-BFO classification 'Clock delta 19 mutant mouse model' is a genetic model
oboInOwl:hasDefinition
Mice having a single base mutation that leads to a loss of exon 19 during an aberrant gene-splicing event, which effectively deletes the coding region for the transactivational domain that is required for Clock-mediated transcription. Clock mutant mice display both hyperactivity and sensorimotor deficits similar to acutely manic patients.