GCLM knockout mouse model
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This is just here as a test because I lose it
Term information
CommentOnHierarchy
No reference ontology for OBO-BFO classification 'GCLM knockout mouse model' is a genetic model
oboInOwl:hasDefinition
Mice models in which gene coding for glutamate-cysteine ligase modifier unit (GCLM) is disrupted. GCLM-KO mice display a range of mania-like behaviors, including enhanced sensitivity to the locomotor stimulating effects of amphetamine, altered social behavior, and impaired sensorimotor gating. In response to mild stress, GCLM-KO mice become more exploratory, risky, and less ‘anxious’ and ‘depressed’.