An amyloidosis that is characterized by a loss of sensation in the extremities, cardiomyopathy, nephropathy, vitreous opacities, and CNS amyloidosis resulting from abnormal deposits of amyloid protein in the body's organs and tissues and has_material_basis_in autosomal dominant inheritance of mutations in the TTR gene. [ http://purl.obolibrary.org/obo/ECO_0007636 url:http://www.ncbi.nlm.nih.gov/books/NBK1194/ url:http://www.paramiloidose.com/en/paramiloidose.php?a=2&id=25 http://purl.obolibrary.org/obo/ECO_0007638 url:http://www.orpha.net/consor4.01/www/cgi-bin/OC_Exp.php?lng=EN&Expert=85451 http://purl.obolibrary.org/obo/ECO_0007646 url:https://www.ncbi.nlm.nih.gov/books/NBK1194/ url:https://www.ncbi.nlm.nih.gov/pubmed/19372706 http://purl.obolibrary.org/obo/ECO_0007637 url:http://ghr.nlm.nih.gov/condition/transthyretin-amyloidosis url:http://en.wikipedia.org/wiki/Transthyretin-related_hereditary_amyloidosis http://purl.obolibrary.org/obo/ECO_0007645 ]