A monogenic disease that has_material_basis_in mutations in genes on the X chromosome. [ http://purl.obolibrary.org/obo/ECO_0007637 url:http://en.wikipedia.org/wiki/Genetic_disorder#X-linked_dominant url:http://ghr.nlm.nih.gov/handbook/inheritance/inheritancepatterns http://purl.obolibrary.org/obo/ECO_0007638 ]