progressive multifocal leukoencephalopathy

progressive multifocal leukoencephalopathy

http://purl.obolibrary.org/obo/DOID_643

A viral infectious disease that involves reactivation of JC polyomavirus in immune-compromised individuals which causes the loss of white matter (which is made up of myelin, a substance the surrounds and protects nerve fibers) in multiple areas of the brain. The symptoms include hemiparesis, aphasia, dysarthria, hemianopia, cognitive impairment and coma. [ http://purl.obolibrary.org/obo/ECO_0007643 url:http://www.merck.com/mmpe/sec16/ch217/ch217f.html http://purl.obolibrary.org/obo/ECO_0007637 url:http://www.ninds.nih.gov/disorders/pml/pml.htm url:http://www.merriam-webster.com/medical/progressive%20multifocal%20leukoencephalopathy ]

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database cross reference

SNOMEDCT_US_2023_03_01:22255007
NCI:C26815
MESH:D007968
ICD10CM:A81.2
ICD9CM:046.3
GARD:7468
UMLS_CUI:C0023524

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DO_rare_slim, DO_infectious_disease_slim, NCIthesaurus

acronym

PML

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disease_ontology

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PML

DOID:643

Term relations

Subclass of:

viral infectious disease
has symptom some hemiparesis
has phenotype some Cognitive impairment
has symptom some dysarthria
has symptom some aphasia
has material basis in some JC polyomavirus
has symptom some coma