glucocorticoid resistance
Go to external page https://bio.scai.fraunhofer.de/ontology/schizophrenia#glucocorticoid_resistance
This is just here as a test because I lose it
Term information
oboInOwl:hasDefinition
An autosomal dominant condition due to mutation(s) in the NR3C1 gene, encoding the glucocorticoid receptor, resulting in decreased receptor affinity to glucocorticoids. Compensatory activation of the hypothalamic- pituitary-adrenal (HPA) axis results in increased mineralocorticoid and androgen production; clinical manifestations of glucocorticoid deficiency are rare.