tertiary amino compound
|
CHEBI_50996 |
|
atypical chronic myeloid leukemia, BCR-ABL1 negative
|
DOID_0060597 |
[A myelodysplastic myeloproliferative neoplasm characterized by the principal involvement of the neutrophil series with leukocytosis and multilineage dysplasia. The neoplastic cells do not have a Philadelphia chromosome or the BCR/ABL fusion gene.] |
myelodysplastic/myeloproliferative neoplasm
|
DOID_4972 |
[A myeloid neoplasm that results_in the overproduction of white blood cells.] |
Nance-Horan syndrome
|
DOID_0060599 |
[A syndrome that has_material_basis_in mutation in the NHS gene on chromosome Xp22 and is characterized by congenital cataract leading to profound vision loss, characteristic dysmorphic features and dental anomalies.] |
syndrome
|
DOID_225 |
[A disease characterized by a group of signs and symptoms that occur together and characterize a particular abnormality.] |
X-linked dominant disease
|
DOID_0080009 |
[A X-linked monogenic disease that has_material_basis_in dominant inheritance.] |
NMD_escaping_variant
|
SO_0002320 |
|
functionally_abnormal
|
SO_0002218 |
|
stop_gained_NMD_triggering
|
SO_0002321 |
|
stop_gained
|
SO_0001587 |
|
NMD_triggering_variant
|
SO_0002319 |
|
stop_gained_NMD_escaping
|
SO_0002322 |
|
frameshift_variant_NMD_triggering
|
SO_0002323 |
|
frameshift_variant
|
SO_0001589 |
|
XFE progeroid syndrome
|
DOID_0060590 |
[A progeroid syndrome that is characterized by aged bird-like facies, lack of subcutaneous fat, dwarfism, cachexia and microcephaly and that has_material_basis_in homozygous mutation in the ERCC4 gene on chromosome 16p13.] |
progeroid syndrome
|
DOID_0081332 |
[A syndrome that is characterized by the premature onset of age-related pathologies.] |
autosomal recessive disease
|
DOID_0050737 |
[An autosomal genetic disease that is characterized by the presence of two mutated copies of the gene, both of which must be present in order for the disease or trait to develop.] |
altered_gene_product_level
|
SO_0002314 |
|
functional_effect_variant
|
SO_0001536 |
|
WHIM syndrome 1
|
DOID_0060591 |
[An immunodeficiency disease that is characterized by neutropenia, hypogammaglobulinemia, and extensive human papillomavirus infection and that has_material_basis_in heterozygous mutation in the CXCR4 gene on chromosome 2q22.] |