primary immunodeficiency disease
|
DOID_612 |
[An immune system disease that results when one or more essential parts of the immune system is missing or not working properly at birth due to a genetic mutation.] |
autosomal dominant disease
|
DOID_0050736 |
[An autosomal genetic disease that is characterized by the presence of one disease-associated mutation of a gene which is sufficient to cause the disease.] |
increased_gene_product_level
|
SO_0002315 |
|
B-cell adult acute lymphocytic leukemia
|
DOID_0060592 |
[An adult acute lymphoblastic leukemia occurring in adults and that has_material_basis_in B lymphocytes.] |
lymphoma
|
DOID_0060058 |
[A hematologic cancer that affects lymphocytes that reside in the lymphatic system and in blood-forming organs.] |
adult acute lymphocytic leukemia
|
DOID_5604 |
[An acute lymphocytic leukemia occurring during adulthood.] |
decreased_gene_product_level
|
SO_0002316 |
|
absent_gene_product
|
SO_0002317 |
|
null_mutation
|
SO_0002055 |
|
altered_gene_product_sequence
|
SO_0002318 |
|
Noonan syndrome 8
|
DOID_0060586 |
[A Noonan syndrome that has_material_basis_in caused by heterozygous mutation in the RIT1 gene on chromosome 1q22.] |
Noonan syndrome
|
DOID_3490 |
[A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.] |
Noonan syndrome 9
|
DOID_0060587 |
[A Noonan syndrome that has_material_basis_in heterozygous mutation in the SOS2 gene on chromosome 14q21.] |
Noonan syndrome 10
|
DOID_0060588 |
[A Noonan syndrome that has_material_basis_in heterozygous mutation in the LZTR1 gene on chromosome 22q11.] |
Yunis-Varon syndrome
|
DOID_0060589 |
[A syndrome characterized by skeletal defects, including cleidocranial dysplasia and digital anomalies, and severe neurologic involvement with neuronal loss. Enlarged cytoplasmic vacuoles are found in neurons, muscle, and cartilage. It is usually lethal in infancy and has_material_basis_in homozygous or compound heterozygous mutation in the FIG4 gene on chromosome 6q21.] |
Protomacleaya
|
NCBITaxon_119225 |
|
Ochlerotatus <genus>
|
NCBITaxon_190765 |
|
Noonan syndrome 2
|
DOID_0060580 |
[A Noonan syndrome characterized by hypertrophic obstructive cardiomyopathy and that has_material_basis_in homozygous or compound heterozygous mutation in the LZTR1 gene on chromosome 22q11.] |
Noonan syndrome 3
|
DOID_0060581 |
[A Noonan syndrome that has_material_basis_in heterozygous mutation in the KRAS gene.] |
Noonan syndrome 4
|
DOID_0060582 |
[A Noonan syndrome that has_material_basis_in heterozygous mutation in the SOS1 gene on chromosome 2p22.] |